The Effect of Antimicrobial Treatment upon the Gill Bacteriome of Atlantic Salmon (Salmo salar L.) and Progression of Amoebic Gill Disease (AGD) In Vivo

Branchial surfaces of finfish species contain a microbial layer rich in commensal bacteria which can provide protection through competitive colonization and production antimicrobial products. Upon disturbance or compromise, pathogenic microbiota may opportunistically infiltrate this protective barrier initiate disease. Amoebic gill disease (AGD) is globally significant health condition affecting salmonid mariculture. The current study examined whether altering the diversity and/or abundance branchial could influence development experimentally induced AGD. Here, we challenged Atlantic salmon (Salmo salar) with Neoparamoeba perurans number scenarios where bacterial community on was altered state instability. Administration oxytetracycline (in-feed) chloramine-T (immersion bath) significantly load taxa upon surface, shifted profile appreciably. AGD severity marginally higher fish previously subjected to treatment following 21 days post-challenge. This research suggests that progression not clearly linked specific present these systems. However, identified associated including known genus (Aliivibrio, Tenacibaculum Pseudomonas) increased as progressed. Elucidation potential role for warranted.